Countdown To 2022 NCAA Tournament: South and Midwest Region Top Seeds and Stats



FairwayJay provides insight, stats & profiles of NCAA Tournament No. 1 and No. 2 seeds in South and Midwest Regions.

NCAA Tournament No. 1 and 2 Seeds South and Midwest Region Profiles 

The March Madness brackets are being filled out, and the picks and pools finalized for the 2022 NCAA Tournament. March Madness tournament betting at leading online sportsbooks is most popular for the opening weekend games with wall-to-wall basketball as teams shoot for a spot in the Sweet Sixteen. 

Number 1 2 seeds preview South MidwestThere are some fundamental keys to NCAA Tournament success as you evaluate the match-ups and stats prior to and during the tournament. As you break down the brackets and match-ups, futures odds and BetOnline each round of the NCAA Tournament, here are some team profiles, stats and odds outlook to track as the top teams advance through the NCAA Tournament. 

The biggest sporting event of the year offers so many action-packed games throughout the tournament, and especially opening weekend. The top teams and seeds will be most popular picks in NCAA Tournament brackets and pools, and I've chipped in some profiles of those teams from the South and Midwest Regions. 

Also, check out the top teams No. 1 and No. 2 seeds and profiles from the East and West Regions

N - Neutral site    A - Away 

NET ranking: takes into account game results, strength of schedule, game location, scoring margin, net offensive and defensive efficiency, and the quality of wins and losses. 

Be sure to get in and enter the Offshore Gaming Association's 2022 March Madness Bracket Challenge. Now in it's 20th year at OSGA, it's free to enter and pays out cash prizes thanks to sponsor BetAnySports.

No. 1 and 2 Seeds South Region 


No. 1 Arizona 

number 1 seeds South MidwestKey Wins: UCLA (2x), USC (A), Illinois (A), Michigan (N)
National Title Odds: +700 
Final Four Odds: +150
KenPom: Top 5 offense and 2 point % shooting and top 10 effective FG%. Top 20 defense and top 10 effective FG% defense (adjusted efficiency ratings)
Twitter: @ArizonaMBB

Arizona's NET ranking is 2, and the Wildcats went 6-3 vs Quad 1 opponents and 9-0 vs Quad 2. Arizona was top 3 in the country in scoring (84.6 PPG).

No. 2 Villanova 

Villanova NCAA previewKey Wins: Tennessee (N), Seton Hall (A), Providence (2x), Marquette (A), UCONN (2x), Creighton (2x)
NCAA Title Odds: +2200 
Final Four Odds: +475
KenPom: Top 10 offense and top 30 defense. No. 1 in free throws (82.3%).
Twitter: @NovaMBB

Villanova's NET ranking is 8, and the Wildcats went 7-6 vs Quad 1 opponents and 10-1 vs Quad 2. 

No.1 and 2 Seeds Midwest Region 


No. 1 Kansas 

Kansas March Madness previewKey Wins: Baylor, Texas Tech (2x), Iowa State (A), Texas, TCU (2x), Michigan State (N)
NCAA Title Odds: +1100 
Final Four: +200
KenPom: Top 10 offense and top 30 defense. 
Twitter: @KUHoops 

Kansas had 12 Quad 1 wins - most in the country. The Jayhawks four Big 12 Quad 1 losses were all on the road, and they lost to Kentucky at home. Kansas has a NET ranking of 6.

No. 2 Auburn 

number 2 seeds NCAA Tournament previewKey Wins: Kentucky, Alabama (2x), Texas A&M, LSU, Murray State, Loyola-Chicago (N), 
NCAA Title Odds +1200 
Final Four: +250
KenPom: Top 25 offense, top 10 defense and defensive FG% and 2 point %. No. 1 in blocks %.  
Twitter: @AuburnMBB 

Auburn has a NET ranking of 11, and the Tigers went 8-5 vs Quad 1 opponents and 7-0 vs Quad 2. 

FairwayJay is a proven sports handicapper including past documented top of the leaderboard college basketball results. FairwayJay chips in additional sports betting coverage and reporting on industry news and events. Read more great insights from FairwayJay and follow him on Twitter: @FairwayJay 


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