NCAA Tournament No. 1 and 2 Seeds East and West Region Profiles 

The March Madness brackets are being filled out, and the picks and pools finalized for the 2022 NCAA Tournament. March Madness tournament betting at leading online sportsbooks is most popular for the opening weekend games with wall-to-wall basketball as teams shoot for a spot in the Sweet Sixteen. 

There are some fundamental keys to NCAA Tournament success as you evaluate the match-ups and stats prior to and during the tournament. As you break down the brackets and match-ups, futures odds and BetOnline each round of the NCAA Tournament, here are some team profiles, stats and odds outlook to track as the top teams advance through the NCAA Tournament. 

The biggest sporting event of the year offers so many action-packed games throughout the tournament, and especially opening weekend. The top teams and seeds will be most popular picks in NCAA Tournament brackets and pools, and I've chipped in some profiles of those teams from the East and West Regions. 

You can also track the No. 1 and No. 2 seeds from the South and Midwest. 

N - Neutral site    A - Away

NET ranking: takes into account game results, strength of schedule, game location, scoring margin, net offensive and defensive efficiency, and the quality of wins and losses.

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No. 1 and 2 Seeds East Region

No. 1 Baylor

Key Wins: Kansas, Villanova, Texas (2x), TCU (A), Iowa State (A), Michigan State (N)
National Title Odds: +1400 
Final Four Odds: +270
KenPom: Top 10 offense and offensive rebounding %, top 15 defense (adjusted efficiency ratings)
Twitter: @BaylorMBB 

Baylor's NET ranking is 4, and the Bears had 10 Quadrant 1 wins - second most in the country. Baylor had 5 Quad 1 losses and went 8-1 vs. Quad 2 opponents. 

No. 2 Kentucky

Key Wins: Kansas (A), Tennessee, LSU, Alabama (2x), Texas A&M (A), North Carolina (N)
NCAA Title Odds: +800 
Final Four Odds: +240
KenPom: Top 5 offense & offensive rebounding %, top 25 defense
Twitter: @KentuckyMBB

Kentucky’s NET ranking is 5, and the Wildcats went 9-7 vs Quad 1 teams and 5-0 vs Quad 2.

No.1 and 2 Seeds West Region

No. 1 Gonzaga

Key Wins: UCLA (N), Texas Tech (N), Texas, St. Mary's, San Francisco (2x)
NCAA Title Odds: +285 
Final Four: -150
KenPom: No. 1 offense and No. 2 effective FG%, top 10 defense and No. 1 effective FG%. No. 1 offense and defense 2-point % shooting. No. 1 scoring (87.8 PPG)
Twitter: @ZagMBB

Gonzaga is a No. 1 NCAA Tournament seed for the third straight season. The Bulldogs have the top No. 1 NET ranking. The Zags went 10-3 vs Quad 1 opponents, and were 20+ point favorites 15 times going 7-8 ATS. 

No. 2 Duke

Key Wins: Gonzaga (N), Kentucky (N), North Carolina (A), Virginia Tech
NCAA Title Odds +1600 
Final Four: +450
KenPom: Top 10 offense, top 10 defense
Twitter: @DukeMBB

Duke has a NET ranking of 12, and the Blue Devils went 6-2 vs Quad 1 opponents and 6-3 vs Quad 2. 

FairwayJay is a proven sports handicapper including past documented top of the leaderboard college basketball results. FairwayJay chips in additional sports betting coverage and reporting on industry news and events. Read more great insights from FairwayJay and follow him on Twitter: @FairwayJay